The treatment of neuropathic pain, an unpleasant condition attributed to nerve damage, has long relied on opioids which sometimes precipitate effects that are worse than the disease itself. As the social stigma associated with Cannabis continues to wear off, the treatment of neuropathic pain is one of the areas where the benefits of the plant have become very apparent. Recent studies have produced scientific evidence that support the efficacy of the plant in managing the condition as well as the actual side effects of conventional treatments.

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Recommended Cannabis Strains for the Treatment of Neuropathic Pain

Pure Power Plant (Hybrid)	Nirvana Pure Power Plant (PPP), a strong F1 hybrid, was developed in the late 90s from a South African Sativa and a fat Indica from the USA. Pure Power Plant's tremendous potential is a prime example of the hybrid vigour often seen in marijuana seeds. This variety is the latest trend among Dutch commercial cannabis growers because of its high yields of valuable marijuana buds. Pure Power Plant has a pleasant pine-like after taste and a powerful social buzz. Effects: Happy, Focussed, Creative, Relaxed, Energetic Medical Uses: Stress, Fatigue, Pain, Headaches, Depression Click Here for More
Jack Herer (Mostly Sativa)	Jack Herer is a blissful, uplifting sativa with mild body effects. This famous strain was named after legendary cannabis activist Jack Herer. Dutch breeders couldn't have created a better strain to pay homage to such an influential figure. Uses are creative uplift and body high. Expect to find yourself relaxed and philosophical after a few puffs. THC 20% CBD 0.1% Lineage Haze Shiva Skunk, Northern Lights Effects: Cerebral, Creativity, Energetic, Euphoric, Happiness, Uplifting Medical Uses: ADD/ADHD, Depression, Fatigue, Headaches, Nausea, Pain, Stress Terpenes Humulene, Limonene, Pinene, Terpinolene Click Here for More
Cannatonic (High CBD Strain)	Cannatonic is a beautiful high-CBD hybrid with ample medical benefits. The strain does feature a little THC, but levels rarely reach over 6%. The CBD content, on the other hand, typically ranges between 6% and 17%. Cannatonic is an extremely relaxing strain without a long-lasting psychoactive high. Rather, this strain produces a. calm, relaxed sensation. You may feel a gentle warming or tingling sensation as the body relaxes, but these are very pleasant and not disruptive. You may still feel a bit of THC's presence, but the higher the CBD content in your strain, the less noticeable it will be. Effects: Cerebral, Focus, Happiness, Pain Relief, Relaxation, Sociable, Tingly, Uplifting Medical Uses Alzheimer's, Anxiety, Arthritis, Bipolar Disorder, Cramps, Crohn's Disease, Depression, Epilepsy, Eye Pressure, Fibromyalgia, Gastrointestinal Disorder, Glaucoma, Headaches, Inflammation, Migraines, Multiple Sclerosis, Muscle Spasms, Muscular Dystrophy, Nausea, Pain, Parkinson's, Phantom Limb Pain, PMS, PTSD, Seizures, Spasticity, Spinal Cord Injury, Stress, Tourette's Syndrome Terpenes: Humulene , Linalool , Myrcene. Pinene Click Here for More
Chemdawg (Mostly Sativa)	Chemdawg is one mysterious strain. The original genetics are unknown, but this legendary hybrid is the suspected parent of many common crowd pleasers, including OG Kush. Chemdawg is a legendary balanced hybrid. This strain is high-yielding and produces almost narcotic effects. It's not uncommon for the THC content in this strain to reach above 20%. This potent hybrid is excellent for those in need of some hardcore pain relief. Yet, the heavy hitting cerebral and body highs are not recommended for beginners. THC 20% CBD 1% Effects: Energetic, Euphoria, Happiness, Relaxation Medical Uses: Depression, Insomnia, Lack Of Appetite, Pain, Stress Terpenes: Caryophyllene , Limonene , Myrcene , Pinene Click Here for More
Critical Hog (Mostly Indica)	Critical Hog from T.H. Seeds is a commercial grower’s dream, producing hefty colas that stay true to its Critical Mass genetics with the added influence of Hog’s Cannabis Cup winning legacy. After crossing the two potent indicas, Critical Hog puts off a sweet aroma of earthy and floral flavors that bring on relaxing body effects.This strain has Critical Mass x HOG Genetics. The CBD content of the strain is Unknown. Effects: Relaxed, Happy, Uplifted, Hungry Medical Uses: Pain, Stress, Depression, Lack of Appetite, Insomnia Click Here for More
Tutankhamon (Mostly Sativa)	Tutankhamon (AKA King Tut) by Pyramid Seeds has kept the sour, skunky smell of its parent strain, AK-47, as well as the sativa-dominant effects, making it a great choice for social outings or creative stimulation. This strain has built a reputation for having high THC levels, and the flavor has hints of fresh fruit and flowers that make this beautiful bud fit for a king! THC 20% + Very High CBD 1-5% Medium Effects: Happy, Energetic, Euphoric, Creative, Uplifted Medical Uses: Depression, Stress, Pain, Insomnia, Lack of Appetite Click Here for More
Train Wreck (Mostly Sativa)	Trainwreck is a mind-bending hybrid with potent sativa effects that hit like a freight train. Mexican and Thai sativas were bred with Afghani indicas to produce this Northern California staple, passing on a sweet lemon and spicy pine aroma. Trainwreck begins its speedy hurtle through the mind with a surge of euphoria, awakening creativity and happiness. Migraines, pain, and arthritis are mowed down by Trainwreck’s THC content, and many patients also use it for relief of anxiety, ADD/ADHD, and PTSD. THC 10-15% (Medium) CBD 0-1% (Low) Effects: Euphoric, Happy, Uplifted, Relaxed, Energetic Medical Uses: Stress, Depression, Pain, Lack of Appitite, Headaches Click Here for More
Super Silver Haze (Mostly Sativa)	Super silver Haze was the cool kid on the block back in the 1990s. Since then, it has only increased in popularity. This happy sativa is known for its strikingly cerebral effects, which are followed by a relaxed body high. This particular strain is popular among consumers who suffer from depression, Chronic fatigue and nausea. THC 20% CBD 0.1 Lineage Northern lights Haze Skunk no.1 Effects: Creativity, Energetic, Euphoria, Happiness, Uplifting Medical Uses Fatigue, Lack Of Appetite, Pain, Stress Terpenes: Caryophyllene Myrcene Terpinolene Click Here for More
Super Silver haze CBD (Mostly Sativa)	Super Silver Haze CBD Feminised Seeds by the cannabis seeds breeder Greenhouse Seed Co., is a Photoperiod Feminised marijuana strain. This Mostly Sativa strain produces a High 500 gr/m2 indoors; 1000 gr. per plant outdoors yield. These seeds are ready to harvest in 70 - 77 days in Mid-October. This Feminised seed grows well in Greenhouse, Indoors, Outdoors conditions. This strain has Skunk x Northern Lights x Haze x CBD Strain Genetics. It has a Medium (10-15%) THC Content. The CBD content of the strain is High (5% +). This strain can be used to treat a variety of medical conditions including, Anxiety, Inflammation, Pain. Click Here for More
Crimea Blue (Mostly Indica)	Crimea Blue is a hybrid strain bred by Barney's Farm that is a cross between Blueberry and Crimean hash plant. This short plant completes flowering in 8 to 9 weeks and produces higher than average yields. These seeds are ready to harvest in 55 - 60 days. This Feminised seed grows well in Greenhouse, Indoors, Outdoors conditions. Additionally it can be expected to grow into a Short plant reaching 70-80 cm. This strain has Turkman x Blueberry Genetics. THC 15-20% High CBD 0-1% Low Effects: Uplifted, Relaxed, Euphoric, Sleepy, Happy Medical Uses: Pain, Eye Pressure, Depression, Stress, Insomnia Click Here for More
White Widow (Mostly Indica)	White Widow is a 1990s hybrid that's only gaining in popularity. It's no surprise, either. This strain is famous for its potent, yet very well-balanced high. The THC content of this strain can reach up to 25%. Effects: Creativity, Euphoria, Happiness, Hunger, Psychedelic, Relaxation, Sociable, Uplifting Medical Uses: ADD/ADHD, Anorexia, Anxiety, Cachexia, Cancer, Crohn's Disease, Depression, HIV/AIDS, Insomnia, Lack Of Appetite, Muscle Spasms, Pain, PMS, PTSD, Stress Terpenes Caryophyllene, Humulene, Limonene, Linalool, Pinene Click Here for More
Purple Afghan Kush (Mostly Indica)	Purple Afghan Kush Feminised Seeds by the cannabis seeds breeder Dinafem Seeds, is a Photoperiod Feminised marijuana strain. This Mostly Indica strain produces a High Indoors: 500 g/m2 & Outdoors: 600-800 g/plant yield. These seeds are ready to harvest in 60 days in late September/early October. This Feminised seed grows well in Greenhouse, Indoors, Outdoors conditions. Additionally it can be expected to grow into a Medium, Tall plant reaching up to 2.5 metres. This strain has Purple Kush x Pre'98 Bubba Kush Genetics. It has a High (15-20%) THC Content. The CBD content of the strain is Low (0-1%). Click here for More

A 2007 study researching the effectiveness of Cannabis in treating neuropathic pain associated with HIV presents one of the most prominent cases for the plant. The study, spearheaded by researchers at the University of California involved 50 subjects who were randomly placed on Cannabis (3.65% THC concentration) or placebo cigarettes three times a day for 5 days. The response to their respective regimes was then recorded using a standardized chronic pain rating system.

34 percent of the patients who smoked Cannabis reported a reduction in daily pain, compared to 17 percent in the placebo group. 52 % of patients in the Cannabis group achieved greater than 30 percent reduction in pain, while 24% in the control group reached the same outcome.  The median pain reduction for the first dosage was 72% for those who used the Cannabis cigarette, compared to just 15% among the placebo group. There were no adverse reactions that were reported (Abrams et al., 2007).

Many studies have produced results that are very consistent with these findings. Another study, conducted in 2014 found that opioid-related deaths were 25% lower in US states that had legalized Cannabis use, indicating that Cannabis or a combination of Cannabis and opioid regimes are safer alternatives than opioids alone (Bachhuber, Saloner, Cunningham & Barry, 2014).

Scientific insight into the efficacy of Cannabis,  depending on the method of delivery is relatively scarce. However, smoked or vaped Cannabis is a preference for most patients and medics. The absorption and synthesis of oral Cannabis is known to be slow and unpredictable but there are methods of ingestion that do not lead to strong psychoactive effects such as micro-dosing tinctures or suppositories.

For patients who are uncomfortable with smoking, there are vaporizers and inhalers, which are just as effective as smoking without the harmful inhalation of combusted plant matter. (McCaffrey, 2014). The analgesic and tissue damage-healing properties of the cannabinoids THC and CBD are responsible for the action of Cannabis against neuropathic pain.

Abrams, D., Jay, C., Shade, S., Vizoso, H., Reda, H., & Press, S. et al. (2007). Cannabis in painful HIV-associated sensory neuropathy: A randomized placebo-controlled trial. Neurology, 68(7), 515-521. doi:10.1212/01.wnl.0000253187.66183.9c

Bachhuber, M., Saloner, B., Cunningham, C., & Barry, C. (2014). Medical Cannabis Laws and Opioid Analgesic Overdose Mortality in the United States, 1999-2010. JAMA Internal Medicine, 174(10), 1668-1673. doi:10.1001/jamainternmed.2014.4005

McCaffrey, P. (2014). Treating Neuropathic Pain With Cannabis: Pro and Con. Pain Research Forum. Retrieved 17 February 2017, from http://www.painresearchforum.org/news/48905-treating-neuropathic-pain-cannabis-pro-and-con

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